The 491 Gallery was a squatted social centre and multi-disciplinary gallery in Leytonstone, London, England, that operated from 2001 to 2013. Taking its name from its street number, 491 Grove Green Road, the former factory was home to a community-led art organisation and served as an exhibition space for a diverse range of artists of different origins working in varied media. It contained a range of art and music studios, which were used to host workshops, classes and musical rehearsals.
The building, originally a factory, was later used as a storage space and warehouse for materials being used to construct the A12 that cuts through Leytonstone and the surrounding areas. Unlike the rest of the surrounding buildings, it and the few neighbouring houses were not subject to compulsory purchase orders and demolition for the A12 site. When in late 2000 the building was abandoned, it became occupied by a group of homeless drug users, who remained in it for some six months. Within a month of their vacating the premises, the building was reoccupied by a group of artists, who spent the next several years turning it into a community space. The neighbouring building, formerly houses, was also occupied, and named Vertigo, after the film by Alfred Hitchcock, a famous resident of Leytonstone.